Chemistry

Breakout companies

start with great

chemistry

We back early-stage founders with a rare blend of technical expertise and commercial instincts.

Current Investments

Pre-Chemistry Investments

PRE

Turning every meeting into structured, actionable intelligence - increasing alignment, and ensuring nothing falls through the cracks.

Helping leading brands build and scale high-performing agents to automate mission-critical customer service workflows with fast, reliable, always-on support.

Replacing legacy help desks with an AI-native ITSM platform, letting teams handle provisioning and support directly in Slack, email, or web to expedite resolution.

"Kristina is one of the sharpest thinkers in venture. She gets to the heart of any issue fast and has been a true partner, helping us land game-changing hires and customers."

"Mark and the team at Chemistry have my back, full stop. It's such a game changer having them in our camp."

"Ethan surprised me with a check over breakfast one morning and from that moment onward, he’s been all in. He showed conviction and passion for what made Twilio special well before any one else did."

"I rolled my eyes for years when VCs said they could be "helpful". But when I started working with Ethan and Chemistry it completely changed my perspective on what's possible."

"Mark is one of the hardest-hustling VCs, and has always been there to help us chase a deal or close a candidate. He’s always ready to pitch in and support where needed most."

Powering live, interactive streaming that turns audiences into communities in real time.

We bring institutional experience and start-up energy….

Chemistry started with a simple belief: early-stage founders deserve better. More focus. More care. More commitment. With shared roots at Bessemer, a16z, and Index - and friendship built along the way - we came together to show up early and go all-in from day one.

team

From the Lab

Elements #3: Chat with Kristen Faulkner (2x Gold Olympian)

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Mark & Ivory at Surf Camp at NeurIPS

Surf Camp at NeurIPS 2025

Team celebrating our one-year anniversary

SF Mayor Daniel Lurie in Chemistry Offices

FrontierAI Reading Club

Elements #2: Chat with Ashwin Sreenivas (Founder, Decagon)

Elements #1: Chat with Brad Lightcap (COO, OpenAI)